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Ovarian Cancer


Book Series:  A Cold Spring Harbor Perspectives in Medicine Collection
Subject Area(s):  Immunology and VaccinesCancer Biology

Edited by James D. Brenton, University of Cambridge; Benjamin G. Neel, NYU Langone Medical Center

Due October 2025 • 250 pages (approx.), illustrated, index
Hardcover •
ISBN  978-1-621822-35-6

  •     Description    
  •     Contents    

Description

Ovarian cancer is a devastating disease that is frequently fatal. This volume examines the molecular basis of the disease within the reproductive system, environmental and genetic risk factors, current treatments and the potential for targeted therapies.

Contents

Preliminary
Preface
Rare Epithelial Ovarian Cancers: Low grade serous and mucinous carcinomas
Olivia Craig, Abhimanyu Nigam, Genevieve V. Dall, and Kylie Gorringe
Ovarian Cancer Therapy
Diana Miao, Ursula A. Matulonis, and Rebecca L. Porter
Prevention of Epithelial Ovarian Cancer
Thomas A. Sellers, Lauren C. Peres, Cassandra Hathaway, and Shelley S. Tworoger
Embryological Insights into the Origin of Epithelial Cancers of the Female Reproductive Tract
Theresa Austria and Louis Dubeau
Genomic Instability, Evolution, and Clonal Dynamics in High-Grade Serous Ovarian Cancer
Ignacio Vazquez-Garcia, Ying Liu, Hongyu Shi, Nicole Rusk, Dmitriy Zamarin, and Sohrab P. Shah
Ovarian Clear Cell Carcinoma (OCCC): An Endometriosis-Associated Cancer with Therapeutic Challenges
Ruby Yun-Ju Huang and Jimmy Jin-Che Lin
The Emerging Role of the Single-Cell and Spatial Tumor Microenvironment in High-Grade Serous Ovarian Cancer
Inga-Maria Launonen, Anna Vähärautio, and Anniina Färkkilä
Harnessing Anti-Tumor Immunity in Ovarian Cancer
Katherine C. Kurnit and Kunle Odunsi
Early Detection of Ovarian Cancer
Naoko Sasamoto and Kevin Elias
Experimental Models for High-Grade Serous Ovarian Cancer

Oscar Pundel and Benjamin G. Neel
Mutational Signatures and Therapy Response in High-Grade Serous Ovarian Carcinoma
Ionut-Gabriel Funingana, Thomas Bradley, and James D. Brenton
Index