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Heart Development and Disease

Book Series:  A Cold Spring Harbor Perspectives in Biology Collection
Subject Area(s):  Developmental BiologyHuman Biology and Disease

Edited by Benoit G. Bruneau, Gladstone Institute of Cardiovascular Disease, University of California, San Francisco; Paul R. Riley, University of Oxford

Due February 2020 • 250 pages (approx.), illustrated, index
Hardcover • $135 108.00
ISBN  978-1-621823-58-2
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  •     Contents    


Development of the heart is a complex process and can lead to serious congenital disease if the process goes awry. This book provides a detailed description of the cell lineages involved in heart development and how their migration and morphogenesis are controlled. It also examines the genetic and environmental bases for congenital heart disease and how model systems are revealing more about the processes involved.


Cardiopharyngeal Progenitor Specification: Multiple Roads to the Heart and Head Muscles
Benjamin Swedlund and Fabienne Lescroart
The onset of cardiac function
Shankar Srinivas
Early cardiac morphogenesis
Vincent Christoffels
Anatomy of a Developing Heart
Tim Mohun
Determinants of Cardiac Growth and Size
Todd R. Heallen, Zachary A. Kadow, Jun Wang, and James F. Martin
Genetic and Epigenetic Control of Heart Development
Brynn N. Akererg and William T. Pu
Long Noncoding RNAs in Cardiac Development
Michael Alexanian and Samir Ounzain
Genome-wide approaches for understanding heart development
Laurie Boyer
Coronary vessel development
Bin Zhou
Formation and Growth of Cardiac Lymphatics During Embryonic Development, Heart Regeneration, and Disease
Dana Gancz, Gal Perlmoter and Karina Yaniv
Development of the Cardiac Conduction System
Samadrita Bhattacharyya and Nikhil V. Munshi
Developmental Pathway of Cardiac Fibroblasts
Michelle D. Tallquist
Cardiac neural crest
Hiroyuki Yamigishi
Epicardium in Heart Development
Yingxi Cao, Sierra Duca, and Jingli Cao
Heart Disease and Development: The Endocardium and Heart Valves
Bailey Dye and Joy Lincoln
Daniela Panakova
Frank Conlon
Andrea Munsterberg
Reptiles as a Model System to Study Heart Development
Bjarke Jensen and Vincent M. Christoffels
Genetic Basis of Human Congenital Heart Disease
Shannon N. Nees and Wendy K. Chung
In Vivo and In Vitro Genetic Models of Congenital Heart Disease
Uddalak Majumdar, Jun Yasuhara and Vidu Garg
Environmental Risk Factors for Congenital Heart Disease
Jacinta Isabelle Kalisch-Smith, Nikita Ved, and Duncan Burnaby Sparrow